A Cases of Paraganglioma in Bladder of Patient who Visited with Acute Renal Failure

Korean Journal of Nephrology 2007;26(6):753-757.

In Seok Seo, M.D.1, Yang Hoon Nam, M.D.1, Ji Hwan Lim, M.D.1 , Jun Hyuk Choi, M.D.1 Jang Eon Kim, M.D.1, Jin Ho Choi, M.D.1 , Ji Min Oh, M.D.1 , Kyu Heum Kwon, M.D.1 Su Jin Yoon, M.D.1 and Yun Kyung Lee, M.D.2

Department of Internal Medicine¹
Pathology²
Seoul Medical Center

증례 : 급성 신부전으로 내원하여 진단된 방광의 부신경절종 1예

서인석1 남양훈1 임지환1 최준혁1 김장언1 최진호1 오지민1 권규흠1 윤수진1 이윤경2

서울의료원 내과1, 진단병리과2

Abstract

Pheochromocytoma is a catecholamines secreting tumor that usually appears in the adrenal medulla, sympathetic ganglia and extra-adrenal chromaffin tissue. About 10% of this disease is detected in the extra-adrenal chromaffin tissue which is called paraganglioma. The three major clinical symptoms of pheochromocytoma are headache, syncope and hypertension. Approximately 0.1% of hypertensive patients have pheochromocytoma. The extra-adrenal paraganglioma is found in abdominal sympathetic nerve ganglion or Zukerkandle's organ with great frequency, but it also appears, albeit rare, in the cervical ganglion, thoracic cavity, bladder, and pelvic cavity. Some cases of paraganglioma in bladder are being reported internationally, but domestic reports are rare. We report a case of paraganglioma originating in the urinary bladder of patient who visited with acute renal failure associated with malignant hypertension. We treated him with phenoxybenzamine and later with partial cystectomy. High blood pressure was well controlled and acute renal failure was resolved.

Key Words: araganglioma, Bladder, Malignant hypertension, Acute renal failure